All vulnerabilities
CVE-2026-100845GHSA-wg9g-w2j2-8pgrPYSEC-2026-4020

MONAI before 1.6.0 Remote Code Execution via NumpyReader

Project-MONAI MONAIPyPILibraries & packages
Open in ThreatlineRecord JSON
CVSS
8.5High
ExploitationPublic exploit codeCISA's assessment says proof of concept code is public, assessed 28 Sep 2026. Not in the KEV catalogCISA via CVE List
Exploit odds (EPSS)0.14%Chance of exploitation activity in the next 30 days, higher than 3% of CVEs. Scored 23 Oct 2026FIRST EPSS
Fixed in1.6.0Fixed versionCVE List
Published27 Sep 2026Updated 1 Oct 2026CVE List

What fixes it

  • 1.6.0MONAICVE List
  • 1.6.0monai, PyPIOSVpip install "monai>=1.6.0"

A fixed version on one release line is not the upgrade target for every line. Check your exact version and any vendor backports.

Description

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

Text from CVE List

Affected versions 46

  • MONAIaffected: all versions before 1.6.0CVE List
  • MONAIunaffected: 1.6.0CVE List
  • monai, PyPIfrom first release, fixed in 1.6.0OSV
  • monai, PyPI0.0.1OSV
  • monai, PyPI0.1.0OSV
  • monai, PyPI0.2.0OSV
  • monai, PyPI0.3.0OSV
  • monai, PyPI0.4.0OSV
  • monai, PyPI0.5.0OSV
  • monai, PyPI0.5.1OSV
  • monai, PyPI0.5.2OSV
  • monai, PyPI0.5.3OSV
  • monai, PyPI0.6.0OSV
  • monai, PyPI0.7.0OSV
  • monai, PyPI0.8.0OSV
  • monai, PyPI0.8.1OSV
  • monai, PyPI0.9.0OSV
  • monai, PyPI0.9.1OSV
  • monai, PyPI1.0.0OSV
  • monai, PyPI1.0.1OSV
  • monai, PyPI1.1.0OSV
  • monai, PyPI1.2.0OSV
  • monai, PyPI1.3.0OSV
  • monai, PyPI1.3.1OSV
  • monai, PyPI1.3.2OSV
  • monai, PyPI1.3.2rc1OSV
  • monai, PyPI1.3.3rc1OSV
  • monai, PyPI1.4.0OSV
  • monai, PyPI1.4.0rc1OSV
  • monai, PyPI1.4.0rc10OSV
  • monai, PyPI1.4.0rc11OSV
  • monai, PyPI1.4.0rc12OSV
  • monai, PyPI1.4.0rc2OSV
  • monai, PyPI1.4.0rc3OSV
  • monai, PyPI1.4.0rc4OSV
  • monai, PyPI1.4.0rc5OSV
  • monai, PyPI1.4.0rc6OSV
  • monai, PyPI1.4.0rc7OSV
  • monai, PyPI1.4.0rc8OSV
  • monai, PyPI1.4.0rc9OSV
  • monai, PyPI1.4.1rc1OSV
  • monai, PyPI1.5.0OSV
  • monai, PyPI1.5.0rc1OSV
  • monai, PyPI1.5.1OSV
  • monai, PyPI1.5.2OSV
  • monai, PyPI1.5.2rc1OSV

References 2